ABR 抗体 (Middle Region)
Quick Overview for ABR 抗体 (Middle Region) (ABIN4886413)
抗原
See all ABR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-407, Middle Region
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原理
- Anti-ABR Antibody Picoband®
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序列
- HPFPDHELED MKMKISALKS EIQKEKANKG QSRAIERL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ABR Antibody Picoband® (ABIN4886413). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ABR, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Active BCR-Related (ABR) (C-Term) antibody
ABR 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Active BCR-Related (ABR) (AA 797-859) antibodyABR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Active BCR-Related (ABR) antibodyABR 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Active BCR-Related (ABR) (AA 750-859) antibodyABR 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Active BCR-Related (ABR) (AA 1-859) antibodyABR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. Heisterkamp, N., Kaartinen, V., van Soest, S., Bokoch, G. M., Groffen, J. Human ABR encodes a protein with GAP-rac activity and homology to the DBL nucleotide exchange factor domain. J. Biol. Chem. 268: 16903-16906, 1993. 2. Heisterkamp, N., Morris, C., Groffen, J. ABR, an active BCR-related gene. Nucleic Acids Res. 17: 8821-8831, 1989. 3. McDonald, J. D., Daneshvar, L., Willert, J. R., Matsumura, K., Waldman, F., Cogen, P. H. Physical mapping of chromosome 17p13.3 in the region of a putative tumor suppressor gene important in medulloblastoma. Genomics 23: 229-232, 1994. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ABR (Active BCR-Related (ABR))
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别名
- ABR
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背景
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Synonyms: Active breakpoint cluster region-related protein,ABR,
Tissue Specificity: Highly enriched in the brain. Much weaker expression in heart, lung and muscle.
Background: This ABR gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.
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分子量
- 98 kDa
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基因ID
- 29
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UniProt
- Q12979
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途径
- Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity
抗原
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