CD34 抗体 (Biotin)
Quick Overview for CD34 抗体 (Biotin) (ABIN488155)
抗原
See all CD34 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.
-
交叉反应 (详细)
- Species reactivity (tested):Human
-
产品特性
- Synonyms: Hematopoietic progenitor cell marker, Hematopoietic progenitor cell antigen CD34
-
免疫原
- Permanent human cell line derived from peripheral leucocytes of a patient suffering fromchronic myeloid leukaemia
-
亚型
- IgG1
-
-
-
-
应用备注
-
Indirect immunofluorescence analysis by Flow cytometry (1: 200 as starting point.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- CD34
-
别名
- CD34
-
背景
- CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker
-
基因ID
- 947
-
UniProt
- P28906
抗原
-