RAMP1 抗体 (AA 84-148)
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Quick Overview for RAMP1 抗体 (AA 84-148) (ABIN488104)
抗原
See all RAMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-148
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特异性
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Recognizes RAMP1
Cellular Localization: Membrane, Single-pass type I membrane protein. -
交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Antigen-Affinity Chromatography.
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免疫原
- Amino Acids 84-148 of Human RAMP1
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应用备注
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Western blot. Positive Controls: HepG2
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.87 mg/mL
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缓冲液
- 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted at (in aliquots) at -20 °C.
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- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
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别名
- RAMP1
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背景
- The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.Synonyms: CRLR activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, RAMP-1, Receptor activity-modifying protein 1
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分子量
- 17 kDa
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基因ID
- 10267, 9606
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UniProt
- O60894
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途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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