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BAIAP2L1 抗体 (AA 1-226)

This anti-BAIAP2L1 antibody is a 兔 多克隆 antibody detecting BAIAP2L1 in WB, IF 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN488102
发货至: 中国

Quick Overview for BAIAP2L1 抗体 (AA 1-226) (ABIN488102)

抗原

See all BAIAP2L1 抗体
BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

适用

人, 小鼠, 大鼠

宿主

  • 26
  • 3

克隆类型

  • 26
  • 3
多克隆

标记

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BAIAP2L1 antibody is un-conjugated

应用范围

  • 17
  • 13
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-226

    特异性

    Recognizes BAIAP2L1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse (94 %) and Rat (94 %).
    Species reactivity (tested):Human.

    纯化方法

    Antigen-Affinity Chromatography

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 226 of BAIAP2L1 Genename: BAIAP2L1
  • 应用备注

    Western blot: 1/500-1/3000. Positive Controls: 293T, A431, HeLa, HepG2. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.55 mg/mL

    缓冲液

    0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C.
  • 抗原

    BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

    别名

    BAIAP2L1

    背景

    This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq].Synonyms: BAI1-associated protein 2-like 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, IRTKS, Insulin receptor tyrosine kinase substrate

    基因ID

    55971, 9606

    UniProt

    Q9UHR4

    途径

    Regulation of Actin Filament Polymerization
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