CRYbA4 抗体 (N-Term)
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Quick Overview for CRYbA4 抗体 (N-Term) (ABIN488078)
抗原
See all CRYbA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-185, N-Term
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特异性
- Recognizes Beta-crystallin A4 (1-150).
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交叉反应 (详细)
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Species reactivity (expected):Mouse (91 %), Rat (91 %), Bovine (94 %), Dog (94 %), Monkey (96 %).
Species reactivity (tested):Human, Mouse. -
纯化方法
- Antigen-Affinity Chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 185 of Beta-Crystallin A4 Genename: CRYBA4
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应用备注
- This antibody is suitable for use in Immunofluorescence/Immunocytochemistry andWestern blotting. Recommended Dilutions: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol and 0.01 % Thimerosal as preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- CRYbA4 (Crystallin, beta A4 (CRYbA4))
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别名
- beta-Crystallin A4
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背景
- Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.Synonyms: Beta-A4 crystallin, CRYBA4
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分子量
- 22 kDa
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基因ID
- 1413, 9606
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UniProt
- P53673
抗原
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