Integrin Alpha2b 抗体 (FITC)
Quick Overview for Integrin Alpha2b 抗体 (FITC) (ABIN4880071)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
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纯化方法
- Purified on protein A from tissue culture supernatant.
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免疫原
- Homogenized human medulloblastoma tissue.
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亚型
- IgG1
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应用备注
- Optimal antibody dilution should be determined by titration
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说明
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Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link®, supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Integrin Alpha2b (CD41)
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别名
- CD41
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基因ID
- 3689
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OMIM
- 607759
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UniProt
- P20701
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途径
- Integrin Complex
抗原
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