Sorting Nexin 1 抗体 (Internal Region)
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Quick Overview for Sorting Nexin 1 抗体 (Internal Region) (ABIN487988)
抗原
See all Sorting Nexin 1 (SNX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody is expected to recognize isoform a and c (NP_003090.2, NP_690039.1.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-TNSSKPQPTYEELE, from the internal region of the protein sequence according to NP_003090.2, NP_690039.1.
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应用备注
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Peptide ELISA: 1/64000. Western blot: Approx 75 kDa band observed in Human lysates of cell line HeLa (calculatedMW of 59.5 kDa according to NP_003090.2). The observed molecular weight corresponds toearlier findings with different antibodies from other commercial sources. Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Sorting Nexin 1 (SNX1)
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别名
- Sorting Nexin-1 (SNX1)
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背景
- Sorting nexin 1 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
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基因ID
- 6642
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NCBI登录号
- NP_003090
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UniProt
- Q13596
抗原
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