CCAR1 抗体 (Internal Region)
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Quick Overview for CCAR1 抗体 (Internal Region) (ABIN487983)
抗原
See all CCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to CCAR1.
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交叉反应 (详细)
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Species reactivity (expected):Canine, Bovine, Porcine.
Species reactivity (tested):Mouse, Rat. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence RYCKERPSKDKE, from the internal region (near C-Terminus) of the protein sequence according to NP_060707.2.
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应用备注
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Peptide ELISA: 1/16000. Western blot: Approx 120 kDa band observed in Mouse and Rat Skeletal Muscle lysates(calculated MW of 130 kDa according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1 - 3 μg/mL. An additional band of unknown identity was also consistently observed at 30 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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别名
- CCAR1
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背景
- DIS is thought to be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Therefore DIS would have a role in cell cycle progression and/or cell proliferation.Synonyms: CARP1, Cell cycle and apoptosis regulatory protein 1, Cell division cycle and apoptosis regulator protein 1, DIS, Death inducer with SAP domain
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基因ID
- 55749
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NCBI登录号
- NP_060707
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UniProt
- Q8IX12
抗原
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