TJP1 抗体 (Internal Region)
Quick Overview for TJP1 抗体 (Internal Region) (ABIN487963)
抗原
See all TJP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to zonula occludens 1 protein.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-PKPTSQNQFSEHDKT, from the internal region of the protein sequence according to NP_003248.3, NP_783297.2.
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应用备注
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Peptide ELISA: 1/128000. Western blot: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TJP1 (Tight Junction Protein 1 (TJP1))
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别名
- ZO-1 / Tight Junction Protein 1
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背景
- Zona Occludens or tight junctions are plasma membrane structures that seal together the perimeters of polarized epithelial cell monolayers and provide the cellular barrier necessary to maintain vectoral secretion, absorption and transport, often defining luminal and intracellular space. Four tight junction specific proteins have been identified (ZO1, ZO2, ZO3 and occludin). ZO1 was the first protein shown to be specifically associated with the tight junction and remains the standard marker for these structures.Synonyms: Tjp1, Zo1, Zona occludens protein 1, Zonula occludens protein 1
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基因ID
- 7082
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NCBI登录号
- NP_003248
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UniProt
- Q07157
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途径
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
抗原
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