CAMP 抗体
This anti-CAMP antibody is a Sheep Polyclonal antibody detecting CAMP in EIA. Suitable for .
Quick Overview for CAMP 抗体 (ABIN487626)
抗原
See all CAMP (cAMP) 抗体
CAMP (cAMP)
(Cyclic Adenosine Monophosphate (cAMP))
适用
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宿主
绵羊
克隆类型
多克隆
标记
This CAMP antibody is un-conjugated
应用范围
Enzyme Immunoassay (EIA)
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纯化方法
- Ig Fraction
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免疫原
- Cyclic AMP-BSA
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亚型
- IgG
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应用备注
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ELISA: 6.05 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 6.05mg/mL (U.V. abs at 280nm)
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缓冲液
- 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CAMP (cAMP) (Cyclic Adenosine Monophosphate (cAMP))
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别名
- cAMP / Cyclic AMP
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物质类
- Chemical
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背景
- Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery.
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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