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PDGFRB 抗体

PDGFRB 适用: 人 IF, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 18A2 unconjugated
产品编号 ABIN487424
发货至: 中国
  • 抗原 See all PDGFRB 抗体
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PDGFRB antibody is un-conjugated
    应用范围
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Thisantibody recognizes CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
    交叉反应 (详细)
    Species reactivity (tested):Human
    产品特性
    Synonyms: PDGF-R-beta, PDGF Receptor beta, Beta-type platelet-derived growth factor receptor, CD140antigen-like family member B
    纯化方法
    Protein A affinity chromatography
    纯度
    > 95 % pure by SDS-PAGE
    免疫原
    CD140b-transfected NIH 3T3 cells
    克隆位点
    18A2
    亚型
    IgG1
    Top Product
    Discover our top product PDGFRB Primary Antibody
  • 应用备注
    Flow cytometry. Immmunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    别名
    CD140b / PDGFRB (PDGFRB 产品)
    背景
    CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.Synonyms: Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, PDGF Receptor beta, PDGF-R-beta
    基因ID
    5159
    UniProt
    P09619
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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