Defensin 抗体
This 小鼠 单克隆 anti-Defensin antibody (Clone Def-3) specifically detects Defensin in IHC 和 IHC (p). The antibody is reactive with 人 samples.
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产品编号 ABIN481654
发货至:
中国
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Contact Info
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中国
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北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for Defensin 抗体 (ABIN481654)
抗原
See all Defensin (DEF) products
Defensin (DEF)
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
Def-3
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特异性
- Several defensins are recognized, the epitope has not been further characterized. Biological functions: Various functions have been described for defensins. They are antibacterial, antifungal, chemotactic for monocytes, inhibitory for ACTH-induced corticosteroid synthesis and cytotoxic for cells. Defensins are inhibited by glucosaminoglycans (self protection for cells) and high concentrations of Calpha 2+ ions. Biochemistry: Defensins are a group of cyclic peptides containing 29-35 amino acids (MW < 3500) which tend to form aggregates. The molecules are protease resistant. The defensin content of azurophilic granules in neutrophils is approximately 30 % of the total protein. Specificity: Human: Defensin 1-3 (HNP-1 to HNP-3) in human neutrophils. Synthetic defensin-1 and -2 (Bachem, Bubendorf CH) stain also positively. Not tested with Defensin-4. A side reaction to elastin has been observed in humans. Other: not tested. Defensins have been described in rabbits (NP-1 to NP-5, NP3a = Corticostatin), and in mice (cryptodin).
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纯化方法
- Affinity purified
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免疫原
- Native defensins
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应用备注
- Approved: IHC, IHC-P (1:1000)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.5 mL distilled water
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4°C.
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- Defensin (DEF)
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别名
- DEF / Defensin
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途径
- Production of Molecular Mediator of Immune Response
抗原
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