PAK1/2 抗体 (pSer144, Ser141)
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北京 101111
Quick Overview for PAK1/2 抗体 (pSer144, Ser141) (ABIN479635)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer144, Ser141
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特异性
- Recognizes Ser144 phosphorylated PAK1 and Ser141 phosphorylated PAK2. This antibody also recognizes Ser139 phosphorylated PAK3 but does not cross-react with phosphorylated PAK4-6. The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase and growth factor-induced neurite outgrowth. Species cross-reactivity: Human and guinea pig, predicted to react with rat and mouse due to 100 % sequence homology.
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纯化方法
- Protein A purified
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免疫原
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KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser144 of human PAK1.
Type of Immunogen: Synthetic phospho-peptide -
亚型
- IgG
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应用备注
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Approved: WB (1:1000)
Usage: Suitable for use in Western Blot. Western Blot: 1:1000. Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, 50 % glycerol.
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- PAK1/2 (P21 Protein (Cdc42/Rac)-Activated Kinase 1/2 (PAK1/2))
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别名
- PAK1/PAK2
抗原
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