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EBV LMP2A 抗体

The 大鼠 单克隆 anti-EBV LMP2A antibody (Clone 15F9) (ABIN472092) specifically detects EBV LMP2A in IHC (p), WB 和 IHC. The antibody is reactive with Epstein-Barr Virus (EBV) samples.
产品编号 ABIN472092
发货至: 中国
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Quick Overview for EBV LMP2A 抗体 (ABIN472092)

抗原

EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))

适用

Epstein-Barr Virus (EBV)

宿主

  • 2
大鼠

克隆类型

  • 1
单克隆

标记

  • 2
This EBV LMP2A antibody is un-conjugated

应用范围

Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

15F9
  • 特异性

    Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.

    纯化方法

    Affinity purified

    免疫原

    Bacterial TrpE-LMP2A fusion protein.

    Type of Immunogen: Fusion protein

    亚型

    IgG1
  • 应用备注

    Approved: IHC, IHC-P, WB (1:100 - 1:1000)

    Usage: Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer  pH 6.0 is recommended for this purpose.

    说明

    Target Species of Antibody: Epstein-Barr Virus

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Short term: -20°C
    Long term: -20°C.
  • 抗原

    EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))

    别名

    EBV LMP2A

    物质类

    Viral Protein
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