EBV LMP2A 抗体
This anti-EBV LMP2A antibody is a 大鼠 单克隆 antibody detecting EBV LMP2A in IHC (p), WB 和 IHC. Suitable for Epstein-Barr Virus (EBV).
Quick Overview for EBV LMP2A 抗体 (ABIN472092)
抗原
EBV LMP2A
(Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
适用
Epstein-Barr Virus (EBV)
宿主
大鼠
克隆类型
单克隆
标记
This EBV LMP2A antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)
克隆位点
15F9
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特异性
- Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.
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纯化方法
- Affinity purified
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免疫原
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Bacterial TrpE-LMP2A fusion protein.
Type of Immunogen: Fusion protein -
亚型
- IgG1
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应用备注
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Approved: IHC, IHC-P, WB (1:100 - 1:1000)
Usage: Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. -
说明
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Target Species of Antibody: Epstein-Barr Virus
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
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别名
- EBV LMP2A
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物质类
- Viral Protein
抗原
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