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Desmoglein 1/2 抗体 (C-Term)

DSG1/2 适用: Cow, 人, 小鼠, 大鼠 IHC, IHC (fro), IHC (p), WB, IF 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN470806
发货至: 中国
  • 抗原 See all Desmoglein 1/2 (DSG1/2) products
    Desmoglein 1/2 (DSG1/2)
    抗原表位
    • 1
    • 1
    • 1
    C-Term
    适用
    Cow, 人, 小鼠, 大鼠
    宿主
    • 2
    小鼠
    克隆类型
    • 2
    单克隆
    标记
    • 2
    This Desmoglein 1/2 antibody is un-conjugated
    应用范围
    Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells, does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines, bovine BMGE+H, BMGE-H, MDBK.
    纯化方法
    Protein A purified
    免疫原
    Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.

    Type of Immunogen: Protein
    亚型
    IgG1
  • 应用备注
    Approved: IF, IHC, IHC-Fr, IHC-P, WB

    Usage: Suitable for use in Immunohistochemistry (frozen sections, paraffin-embedded tissue after microwave treatment), Western Blot, Cryo, Paraffin (Microwave), Immunofluorescence microscopy. Immunohistochemistry: 1:10 with PBS,  pH 7.4, Incubation Time 1 h at RT, extended with paraffin.
    说明

    Target Species of Antibody: Bovine

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    deionized water
    浓度
    Lot specific
    缓冲液
    Lyophilized.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term: 4°C
    Long term: Add glycerol (40-50%) -20°C.
  • 抗原
    Desmoglein 1/2 (DSG1/2)
    别名
    Desmoglein 1/2 (DSG1/DSG2) (DSG1/2 产品)
    别名
    DSG1 antibody, desmoglein 1 antibody, DSG1 antibody
    背景
    This antibody detects: DSG1+2 / Desmoglein 1+2
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