PTCHD2 抗体 (Middle Region)
PTCHD2
适用: 人, 小鼠, 大鼠
WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all PTCHD2 抗体
- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTCHD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid synthetic peptide from near the center of human PTCHD2
- 亚型
- IgG
- Top Product
- Discover our top product PTCHD2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
- 别名
- PTCHD2 (PTCHD2 产品)
- 别名
- DISP3 antibody, G630052C06Rik antibody, RNDEu-2 antibody, RGD1305820 antibody, dispatched RND transporter family member 3 antibody, patched domain-containing protein 2 antibody, si:dkey-32e23.6 antibody, DISP3 antibody, LOC100082708 antibody, si:dkey-32e23.6 antibody, disp3 antibody, Disp3 antibody
- 背景
- PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3
- 基因ID
- 57540
- UniProt
- Q9P2K9
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