PTCHD2 抗体 (Middle Region)
This anti-PTCHD2 antibody is a 兔 多克隆 antibody detecting PTCHD2 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
Quick Overview for PTCHD2 抗体 (Middle Region) (ABIN4620591)
抗原
See all PTCHD2 抗体
PTCHD2
(Patched Domain Containing 2 (PTCHD2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PTCHD2 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- Middle Region
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide from near the center of human PTCHD2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
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别名
- PTCHD2
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背景
- PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3
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基因ID
- 57540
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UniProt
- Q9P2K9
抗原
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