beta Amyloid 抗体
Quick Overview for beta Amyloid 抗体 (ABIN459388)
抗原
See all beta Amyloid (Abeta) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
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预测反应
- rat
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产品特性
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Expected / apparent Molecular Weight of the Antigene: 4.5 kDa
OMAB antibody is a versatile tool within research of Alzheimer’s disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers. OMAB antibody has been purified by by ion-exchange chromatography. -
纯化方法
- affinity purified
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免疫原
- partly aggregated, recombinant peptide corresponding to the human Abeta (1-40/42). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V. The epitope is 3-8.
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亚型
- IgM
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anti-Amyloid beta (Abeta) (C-Term) antibody
Abeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9E8-1A3 unconjugated
anti-Amyloid beta (Abeta) (AA 711-760) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) (Ser15) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人 WB, ELISA, IHC, IP, IEM 宿主: 兔 Chimeric 6E10 unconjugated Recombinant Antibody
anti-Amyloid beta (Abeta) (pThr743) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal AB9 unconjugated
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应用备注
- coating antibody at 2 μg/mL (ELISA), 1: 500 (IHC)
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说明
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OMAB antibody is a versatile tool within research of Alzheimer's disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μL of sterile water.
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缓冲液
- PBS without any additives as carrier proteins or sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
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储存条件
- 4 °C
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储存方法
- store lyophilized/reconstituted at 4°C. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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别名
- Amyloid beta oligomer-specific
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背景
- Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
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分子量
- 4.5 kDa
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途径
- Inflammasome
抗原
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