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PF4 抗体

PF4 适用: 人 ELISA, ID, IEP, Neph, RID 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN458158
发货至: 中国
  • 抗原 See all PF4 抗体
    PF4 (Platelet Factor 4 (PF4))
    适用
    • 63
    • 14
    • 12
    • 1
    宿主
    • 63
    • 18
    • 3
    • 1
    • 1
    克隆类型
    • 67
    • 19
    多克隆
    标记
    • 42
    • 15
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PF4 antibody is un-conjugated
    应用范围
    • 63
    • 35
    • 33
    • 14
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunodiffusion (ID), Immunoelectrophoresis (IEP), Nephelometry (Neph), Radial Immunodiffusion (RID)
    特异性
    Inter-species cross-reactivity is a normal feature of antibodies to serum proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail. In double radial immunodiffusion a reaction has been observed with bovine, cat, dog and monkey.
    产品特性
    Precipitating polyclonal rabbit antiserum to human platelet factor 4
    纯化方法
    Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
    免疫原
    Platelet factor 4 is a low molecular weight (MW 7,800) heat stable protein, secreted by alpha granules of the platelets. Purified platelet factor 4 isolated from pooled human serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
    亚型
    IgG
    Top Product
    Discover our top product PF4 Primary Antibody
  • 应用备注
    In precipitating techniques as electroimmunodiffusion (Laurell), immunoelectrophoresis and single and double radial immunodiffusion to identify the presence platelet factor 4. This antiserum has not been tested in more sensitive assays as nephelometry, ELISA or use in immunohistology, but this does not exclude such use if proper controls are included. Measurement of platelet factor 4 is of significance for diagnosis of platelet disorders involving platelet alpha granules and to demonstrate increased platelet secretion in vivo. Reduced levels are measured in gray platelet syndrome, whereas elevated levels have been reported in cases as coronary artery disease, myocardial infarction, disseminated intravascular coagulation, cerebrovascular disease and cancer.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added. Antibody titre: The amount of platelet factor 4 precipitated by 1 ml antiserum is approximately 0.1 mg.
    缓冲液
    Delipidated, heat inactivated, lyophilized, stable whole antiserum
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.
  • 抗原
    PF4 (Platelet Factor 4 (PF4))
    别名
    Platelet Factor 4 (PF4 产品)
    别名
    CXCL4 antibody, PF-4 antibody, SCYB4 antibody, Cxcl4 antibody, Scyb4 antibody, Pf4a antibody, RATPF4A antibody, PF4A antibody, CXCL4L1 antibody, CXCL4V1 antibody, PF4-ALT antibody, SCYB4V1 antibody, PF4 antibody, platelet factor 4 antibody, platelet factor 4 variant 1 antibody, PF4 antibody, Pf4 antibody, LOC703451 antibody, PF4V1 antibody, LOC100524373 antibody, LOC102181854 antibody, LOC100630489 antibody
    背景
    The reactivity of the antiserum is restricted to platelet factor 4 as tested in immunoelectro-phoresis and radial immunodiffusion. A characteristic single precipitin line is obtained with normal serum which shows a reaction of identity with the precipitin line with purified immunogen
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