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alpha 2 Antiplasmin 抗体

SERPINF2 适用: 人 IEP, ID, RID 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN458138
发货至: 中国
  • 抗原 See all alpha 2 Antiplasmin (SERPINF2) 抗体
    alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
    适用
    • 55
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    宿主
    • 51
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    克隆类型
    • 60
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    多克隆
    标记
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    This alpha 2 Antiplasmin antibody is un-conjugated
    应用范围
    • 48
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    Immunoelectrophoresis (IEP), Immunodiffusion (ID), Radial Immunodiffusion (RID)
    特异性
    The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.
    产品特性
    Precipitating polyclonal rabbit antiserum to human alpha-2 antiplasmin
    纯化方法
    Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
    免疫原
    Alpha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65,000.The normal concentration in human plasma is 60 µ g/ml. Platelets contain significant amounts of the protein, which is released along with platelet factor 4, following thrombin stimulation. It can form 1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa, thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic system was detected by the discovery of a congenital deficiency. Alpha-2 antiplasmin has been isolated from pooled plasma. Freund’s complete adjuvant is used in the first step of the immunization procedure.
    亚型
    IgG
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  • 应用备注
    In precipitating techniques as electroimmunodiffusion (Laurell), immunoelectrophoresis and single and double radial immunodiffusion (Mancini, Ouchterlony). Detection of plasmin-antiplasmin complexes in plasma is evident of plasmin formation and fibrinolysis.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added. Antibody titre: Precipitin titre not less than 1:32 when tested against normal human plasma in agar-block immuno-diffus
    缓冲液
    Delipidated, heat inactivated, lyophilized, stable whole serum.
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.
  • 抗原
    alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
    别名
    alpha-2 Antiplasmin (SERPINF2 产品)
    别名
    A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, serpin antibody, AI747498 antibody, Pli antibody, Serpimf2 antibody, serpinf2 antibody, serpinf2l antibody, wu:fd57d08 antibody, Dmrs91 antibody, Pedf antibody, serpin family F member 2 antibody, serpin family F member 1 antibody, serine (or cysteine) peptidase inhibitor, clade F, member 2 antibody, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a antibody, SERPINF2 antibody, Serpinf2 antibody, SERPINF1 antibody, serpinf2a antibody, Serpinf1 antibody
    背景
    The defined antibody reactivity is restricted to alpha-2 antiplasmin as tested at the level of sensitivity of immuno-precipitation techniques. A single precipitin line is obtained in bidimensional electrophoresis, immunoelectrophoresis and double radial immunodiffusion (Ouchterlony) which shows a reaction of full identity with the purified immunogen
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones
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