PRR7 抗体 (Intracellular)
This anti-PRR7 antibody is a 小鼠 单克隆 antibody detecting PRR7 in WB 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
(1 reference)Quick Overview for PRR7 抗体 (Intracellular) (ABIN457438)
抗原
See all PRR7 抗体
PRR7
(Proline Rich 7 (Synaptic) (PRR7))
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
This PRR7 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunocytochemistry (ICC)
克隆位点
TRAP3-10
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抗原表位
- AA 126-253, Intracellular
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原理
- Anti-PRR7 Purified
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特异性
- The mouse monoclonal antibody TRAP3/10 recognizes an epitope located in the C-terminal part of the intracellular domain of PRR7/TRAP3 (amino acids 126-253 of human PRR7 / TRAP3), a 28 kDa proline-rich membrane protein presumably associated with NMDA receptor complex.
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交叉反应 （详细）
- Human, Mouse, Rat
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant C-terminal half of the intracellular domain of human PRR7/TRAP3 (amino acids 126-253)
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亚型
- IgG2a
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anti-Proline Rich 7 (Synaptic) (PRR7) (AA 160-209) antibody
PRR7 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 7 (Synaptic) (PRR7) (Middle Region) antibodyPRR7 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry: Recommended dilution: 10 μg/mL, cell culture fixed with 4 % paraformaldehyde, permeabilized with 0.1 % Triton-X100.
Western blotting: Recommended dilution: 1 μg/mL, positive control: murine brain lysate (red. Laemmli buffer). -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
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: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
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- PRR7 (Proline Rich 7 (Synaptic) (PRR7))
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别名
- PRR7
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背景
- Proline rich 7, synaptic,PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.,TRAP3
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基因ID
- 80758
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UniProt
- Q8TB68
抗原
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