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SELPLG 抗体

This anti-SELPLG antibody is a 小鼠 单克隆 antibody detecting SELPLG in FACS. Suitable for 人.
产品编号 ABIN457437
发货至: 中国

Quick Overview for SELPLG 抗体 (ABIN457437)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SELPLG antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

TC2
  • 原理

    Anti-Hu CD162 Purified

    特异性

    The antibody TC2 reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Human thymocytes

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1.5 - 2.5 μg/mL, positive control: human peripheral blood.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162

    背景

    Selectin P ligand,CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.,PSGL-1, Selectin P ligand, SELPLG, CLA

    基因ID

    6404

    UniProt

    Q14242
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