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VCAM1 抗体

This 小鼠 单克隆 antibody specifically detects VCAM1 in FACS, IP, ELISA 和 IHC (fro). It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN457435
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VCAM1 抗体 (ABIN457435)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

STA
  • 原理

    Anti-Hu CD106 Purified

    特异性

    The mouse monoclonal antibody STA recognizes an extracellular epitope of CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Human DS6 T cell line

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 4-6 μg/mL, positive control: TNF-alpha activated HUVEC cells.
    Immunohistochemistry (frozen sections): Acetone fixation.
    ELISA: Capture mAb for soluble CD106.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Yen, Liao, Hsiao, Kao, Chen, Wu-Hsieh: "Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." in: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).

  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    CD106

    背景

    Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.,VCAM-1, INCAM-100

    基因ID

    7412

    UniProt

    P19320

    途径

    Carbohydrate Homeostasis
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