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VCAM1 抗体

VCAM1 适用: 人 FACS, IP, ELISA, IHC (fro) 宿主: 小鼠 Monoclonal STA unconjugated
产品编号 ABIN457435
发货至: 中国
  • 抗原 See all VCAM1 抗体
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    适用
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    小鼠
    克隆类型
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    单克隆
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    This VCAM1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The mouse monoclonal antibody STA recognizes an extracellular epitope of CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human DS6 T cell line
    克隆位点
    STA
    亚型
    IgG1
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 4-6 μg/mL, positive control: TNF-alpha activated HUVEC cells.
    Immunohistochemistry (frozen sections): Acetone fixation.
    ELISA: Capture mAb for soluble CD106.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Yen, Liao, Hsiao, Kao, Chen, Wu-Hsieh: "Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." in: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).

  • 抗原
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    别名
    CD106 (VCAM1 产品)
    背景
    Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.,VCAM-1, INCAM-100
    基因ID
    7412
    UniProt
    P19320
    途径
    Carbohydrate Homeostasis
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