CILP 抗体 (Internal Region)
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Quick Overview for CILP 抗体 (Internal Region) (ABIN453982)
抗原
See all CILP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody recognizes CILP.
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交叉反应 （详细）
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Species reactivity (expected):Human, Mouse and Canine (Dog).
Species reactivity (tested):Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-NYRRTDHEDPRVK, from the internal region of the protein sequence according to NP_003604.2.
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anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 603-846) antibody
CILP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 604-864) antibodyCILP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 1051-1184) antibodyCILP 适用: 人, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (Internal Region) antibodyVerified CILP 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Antibody Detection Limit Dilution: 1/128000. Western Blot: 0.1-0.3 μg/mL. Approx 150 kDa band observed in rat spinal cord lysates(calculated MW of 130 kDa according to human NP_003604.2 and of 130 kDa according toRat NP_001101631.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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别名
- CILP1
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背景
- CILP, Cartilage Intermediate Layer Protein, is specifically expressed in the articular cartilage intermediate layer (it cannot be found in the superficial nor in the deepest layers) and is involved in scaffolding. Overexpression of this protein may lead to impairment of chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. Antibodies against CILP are detected in patients with early-stage knee osteoarthritis and defects in this gene may be a cause of susceptibility to lumbar disk disease.Synonyms: CILP-1, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein
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基因ID
- 8483
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NCBI登录号
- NP_003604
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UniProt
- O75339
抗原
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