FERMT3 抗体 (C-Term)
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Quick Overview for FERMT3 抗体 (C-Term) (ABIN453975)
抗原
See all FERMT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This URP2 antibody (AP09600PU-N) is expected to recognize both isoforms (NP_113659.3, NP_848537.1).
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-ERARGEELDED, from the C-Terminus of kindlin-3/URP2 (NP_113659.3, NP_848537.1).
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anti-Fermitin Family Member 3 (FERMT3) (AA 1-663) antibody
FERMT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (C-Term) antibodyFERMT3 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 106-371) antibodyFERMT3 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 388-503) antibodyFERMT3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 117-151) antibodyFERMT3 适用: 小鼠 WB 宿主: 兔 Polyclonal RB56300 unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 1-663) antibodyFERMT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (C-Term) antibodyVerified FERMT3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Peptide ELISA: URP2 Antibody Detection limit dilution: 1/2000. Western blot: 1-3 μg/mL. Approx 75 kDa band observed in Human Peripheral BloodMononucleocytes lysates (calculated MW of 75.5 kDa according to NP_113659.3).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- FERMT3 (Fermitin Family Member 3 (FERMT3))
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别名
- FERMT3
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背景
- URP2 is an essential element for platelet integrin activation in hemostasis and thrombosis. Platelets lacking the adhesion plaque protein URP2 cannot activate integrins despite normal Talin expression. As a direct consequence, URP2 deficiency results in severe bleeding and resistance to arterial thrombosis. URP2 binds directly bind to regions of beta-integrin tails and triggers integrin activation.Synonyms: Fermitin family homolog 3, KIND3, Kindlin-3, MIG2-like protein, MIG2B, URP2, Unc-112-related protein 2
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基因ID
- 83706
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NCBI登录号
- NP_113659
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UniProt
- Q86UX7
抗原
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