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CCL7 抗体 (Biotin)

This Biotin-conjugated 小鼠 单克隆 anti-CCL7 antibody (Clone 113) specifically detects CCL7 in EIA. The antibody is reactive with 人 samples.
产品编号 ABIN453919
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL7 抗体 (Biotin) (ABIN453919)

抗原

See all CCL7 抗体
CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

适用

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宿主

  • 42
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小鼠

克隆类型

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  • 29
单克隆

标记

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This CCL7 antibody is conjugated to Biotin

应用范围

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Enzyme Immunoassay (EIA)

克隆位点

113
  • 特异性

    Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Purified Recombinant Human Monocyte Chemotactic Protein-3 (MCP-3).

    亚型

    IgG1
  • 应用备注

    ELISA: This MCP3 antibody Biotin-conjugated can be used as a Tracer/Detection Antibodyin Sandwich ELISA applications for human MCP-3 detection in combination with a Captureantibody (Cat#DM2039)Suggested Capture Coating Dose: 3 μg/wellSubstrate: TMB
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 M PBS, pH 7.0 ± 0.1, 0.1 % Proclin-300, 1 % Gelatin

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE!
  • 抗原

    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

    别名

    MCP3 / CCL7

    背景

    Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

    基因ID

    6354

    NCBI登录号

    NP_006264

    UniProt

    P80098
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