This antibody reacts to Interleukin-16. IL16 antibody clone 323 exhibits no detectable cross-reacting with human albumin serum, Bovine albumin serum and other human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta 1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
ELISA. Western Blot: IL16 antibody at a concentration of 2.5 μg/mL will allow visualization of 1 μg/lane of human IL-16. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
溶解方式
Restore with double distillated water to adjust the final concentration to 1.00 mg/mL.
缓冲液
0.01 M PBS, pH 7.2 without preservatives.
储存液
Without preservative
注意事项
This product is photosensitive and should be protected from light
储存条件
4 °C
储存方法
Store the antibody at 2 - 8 °C. DO NOT FREEZE!
抗原
IL16
(Interleukin 16 (IL16))
别名
Interleukin-16 / IL16
背景
Interleukin-16 (IL16) is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor