Smith Antigen 抗体
Our Local Distributor
北京 101111
Quick Overview for Smith Antigen 抗体 (ABIN453884)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected.
-
-
-
-
应用备注
-
Immunodiffusion. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
溶解方式
- Restore with 2 mL deionized water
-
缓冲液
- 0.01 M Phosphate, 0.11 M Sodium chloride containing 0.02 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- Source material supplied to your facility has been tested for the detection of HIV antibody, Hepatitis B surface antigen, antibody to Hepatitis C, HIV 1 antigen(s), antibody to HTLV - I/II, and syphilis with FDA approved test kits. All units were found to be non- reactive/negative for these tests. Nevertheless, all products from human sources should be handled as potentially infectious.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
-
- Smith Antigen
-
别名
- Sm / Smith Antigen
-
背景
- The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30 % of patients with SLE. This antibody recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. It precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.Synonyms: Human Autoantigens
抗原
-