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Smith Antigen 抗体

This anti- antibody is a Human 多克隆 antibody detecting in ID 和 EIA. Suitable for 人.
产品编号 ABIN453884
发货至: 中国

Quick Overview for Smith Antigen 抗体 (ABIN453884)

抗原

Smith Antigen

适用

宿主

  • 3
Human

克隆类型

  • 2
多克隆

标记

  • 3
非结合性

应用范围

Immunodiffusion (ID), Enzyme Immunoassay (EIA)
  • 纯化方法

    Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected.
  • 应用备注

    Immunodiffusion. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with 2 mL deionized water

    缓冲液

    0.01 M Phosphate, 0.11 M Sodium chloride containing 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    Source material supplied to your facility has been tested for the detection of HIV antibody, Hepatitis B surface antigen, antibody to Hepatitis C, HIV 1 antigen(s), antibody to HTLV - I/II, and syphilis with FDA approved test kits. All units were found to be non- reactive/negative for these tests. Nevertheless, all products from human sources should be handled as potentially infectious.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    Smith Antigen

    别名

    Sm / Smith Antigen

    背景

    The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30 % of patients with SLE. This antibody recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. It precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.Synonyms: Human Autoantigens
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