Protein Tob1 (TOB1) (AA 61-91), (N-Term) 抗体
Our Local Distributor
北京 101111
Quick Overview for Protein Tob1 (TOB1) (AA 61-91), (N-Term) 抗体 (ABIN453856)
抗原
See all Protein Tob1 (TOB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 61-91, N-Term
-
特异性
- This antibody recognizes TOB1 (N-term).
-
纯化方法
- Affinity Chromatography on Protein A
-
免疫原
- KLH conjugated synthetic peptide between 61~91 amino acids from the N-terminal region of Human TOB1 Genename: TOB1
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Protein Tob1 (TOB1)
-
别名
- TOB1
-
背景
- TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.Synonyms: TOB, TROB1, Transducer of erbB-2 1
-
基因ID
- 10140
-
NCBI登录号
- NP_005740
-
UniProt
- P50616
抗原
-