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Protein Tob1 (TOB1) (AA 61-91), (N-Term) 抗体

This anti-Protein Tob1 antibody is a 兔 多克隆 antibody detecting Protein Tob1 in WB, IHC (p), FACS 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN453856
发货至: 中国
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Quick Overview for Protein Tob1 (TOB1) (AA 61-91), (N-Term) 抗体 (ABIN453856)

抗原

See all Protein Tob1 (TOB1) 抗体
Protein Tob1 (TOB1)

适用

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人, 小鼠

宿主

  • 61
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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
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    AA 61-91, N-Term

    特异性

    This antibody recognizes TOB1 (N-term).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 61~91 amino acids from the N-terminal region of Human TOB1 Genename: TOB1

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Protein Tob1 (TOB1)

    别名

    TOB1

    背景

    TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.Synonyms: TOB, TROB1, Transducer of erbB-2 1

    基因ID

    10140

    NCBI登录号

    NP_005740

    UniProt

    P50616
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