SIGLEC12 抗体 (C-Term)
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Quick Overview for SIGLEC12 抗体 (C-Term) (ABIN453827)
抗原
See all SIGLEC12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to SIGLEC12.
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
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免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human SIGLEC12
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anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 503-595) antibody
SIGLEC12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 27-141) antibodySIGLEC12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) antibodySIGLEC12 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 1-595) antibodySIGLEC12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 110-159) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 38-87) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 218-267) antibodySIGLEC12 适用: 人, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (N-Term) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
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别名
- SIGLEC12
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背景
- Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. SIGLEC12 is a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. This protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor.Synonyms: SIGLECL1, SLG, Sialic acid-binding Ig-like lectin 12, Sialic acid-binding Ig-like lectin-like 1, Siglec-12, Siglec-L1
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基因ID
- 89858
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NCBI登录号
- NP_443729
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UniProt
- Q96PQ1
抗原
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