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Importin 11 抗体 (N-Term)

IPO11 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453706
发货至: 中国
  • 抗原 See all Importin 11 (IPO11) 抗体
    Importin 11 (IPO11)
    抗原表位
    • 10
    • 9
    • 8
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 47
    克隆类型
    • 46
    多克隆
    标记
    • 23
    • 6
    • 5
    • 5
    • 4
    • 4
    This Importin 11 antibody is un-conjugated
    应用范围
    • 41
    • 32
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to IPO11.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide selected from the N-term region of human IPO11
    Top Product
    Discover our top product IPO11 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Importin 11 (IPO11)
    别名
    RanBP11 / Importin-11 (IPO11 产品)
    别名
    MGC83107 antibody, IPO11 antibody, slrn antibody, ranbp11 antibody, RanBP11 antibody, 1700081H05Rik antibody, 2510001A17Rik antibody, AI314624 antibody, AW555235 antibody, E330021B14Rik antibody, Ranbp11 antibody, importin 11 S homeolog antibody, importin 11 antibody, importin-11 antibody, ipo11.S antibody, ipo11 antibody, IPO11 antibody, AFUA_1G03590 antibody, BDBG_04626 antibody, LOC100162908 antibody, Ipo11 antibody
    背景
    IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).Synonyms: IPO11, Imp11, Ran-binding protein 11
    基因ID
    51194
    NCBI登录号
    NP_057422
    UniProt
    Q9UI26
    途径
    Protein targeting to Nucleus
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