ADRA2B 抗体 (AA 349-378)
Quick Overview for ADRA2B 抗体 (AA 349-378) (ABIN453503)
抗原
See all ADRA2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 349-378
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特异性
- This antibody recognizes Alpha-2B adrenergic receptor.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 349~378 amino acids from the Center region of Human ADRA2B. Genename: ADRA2B
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anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibody
ADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22486 unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 1-100) antibodyADRA2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 160-174), (C169S), (Extracellular) antibodyADRA2B 适用: 大鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
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别名
- alpha-2B Adrenergic Receptor
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背景
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor
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基因ID
- 151
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NCBI登录号
- NP_000673
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UniProt
- P18089
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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