SERPINC1 抗体 (C-Term)
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Quick Overview for SERPINC1 抗体 (C-Term) (ABIN453366)
抗原
See all SERPINC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Detects Antithrombin III (C-term).
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Antithrombin III antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of Human Antithrombin III.
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应用备注
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ELISA: 1/1,000Western blotting: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C or (in aliquots) at -20 °C for longer.
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- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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别名
- SERPINC1 / Antithrombin-III
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背景
- Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160 mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58 kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties.Synonyms: AT3, ATIII, Serpin C1
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基因ID
- 462
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NCBI登录号
- NP_000479
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UniProt
- P01008
抗原
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