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PABP 抗体 (Middle Region)

This anti-PABP antibody is a 兔 多克隆 antibody detecting PABP in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN453247
发货至: 中国

Quick Overview for PABP 抗体 (Middle Region) (ABIN453247)

抗原

See all PABP (PABPC1) 抗体
PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PABP antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    特异性

    This antibody reacts to PABPC1.

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation

    免疫原

    KLH conjugated synthetic peptide selected from the Center region of human PABPC1
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

    别名

    PABPC1

    背景

    PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.Synonyms: PAB1, PABP-1, PABP1, PABPC2, Poly(A)-binding protein 1, Polyadenylate-binding protein 1

    基因ID

    26986

    NCBI登录号

    NP_002559

    UniProt

    P11940

    途径

    SARS-CoV-2 Protein Interactome
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