PABP 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for PABP 抗体 (Middle Region) (ABIN453247)
抗原
See all PABP (PABPC1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
特异性
- This antibody reacts to PABPC1.
-
纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
-
免疫原
- KLH conjugated synthetic peptide selected from the Center region of human PABPC1
-
-
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
-
别名
- PABPC1
-
背景
- PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.Synonyms: PAB1, PABP-1, PABP1, PABPC2, Poly(A)-binding protein 1, Polyadenylate-binding protein 1
-
基因ID
- 26986
-
NCBI登录号
- NP_002559
-
UniProt
- P11940
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-