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P4HB 抗体 (C-Term)

P4HB 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453246
发货至: 中国
  • 抗原 See all P4HB 抗体
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    抗原表位
    • 21
    • 18
    • 15
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 443-472, C-Term
    适用
    • 105
    • 73
    • 64
    • 23
    • 22
    • 20
    • 20
    • 18
    • 18
    • 16
    • 10
    • 10
    • 8
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    宿主
    • 117
    • 25
    • 2
    克隆类型
    • 108
    • 36
    多克隆
    标记
    • 60
    • 16
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This P4HB antibody is un-conjugated
    应用范围
    • 110
    • 68
    • 45
    • 43
    • 43
    • 36
    • 17
    • 15
    • 13
    • 13
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Protein Disulfide Isomerase.
    纯化方法
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide between 443~472 amino acids from the C-terminal region of Human P4HB. Genename: P4HB
    Top Product
    Discover our top product P4HB Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    别名
    PDI / P4HB (P4HB 产品)
    别名
    DSI antibody, ERBA2L antibody, GIT antibody, P4Hbeta antibody, PDI antibody, PDIA1 antibody, PHDB antibody, PO4DB antibody, PO4HB antibody, PROHB antibody, PDA2 antibody, PDIP antibody, PDIR antibody, ERp59 antibody, Pdia1 antibody, Thbp antibody, p55 antibody, XPDIp antibody, pdi antibody, 1810041F13Rik antibody, AI661267 antibody, Pdip antibody, Pdipl antibody, p58 antibody, prolyl 4-hydroxylase subunit beta antibody, protein disulfide isomerase family A member 2 antibody, prolyl 4-hydroxylase, beta polypeptide antibody, protein disulfide isomerase family A member 2 L homeolog antibody, protein disulfide isomerase associated 2 antibody, prolyl 4-hydroxylase subunit beta L homeolog antibody, protein disulfide-isomerase antibody, P4HB antibody, PDIA2 antibody, P4hb antibody, pdia2.L antibody, Pdia2 antibody, p4hb.L antibody, LOC8281065 antibody
    背景
    P4HB is a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta p55, Protein disulfide-isomerase
    基因ID
    5034
    NCBI登录号
    NP_000909
    UniProt
    P07237
    途径
    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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