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P4HB 抗体 (C-Term)

This anti-P4HB antibody is a 兔 多克隆 antibody detecting P4HB in WB, FACS, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN453246
发货至: 中国

Quick Overview for P4HB 抗体 (C-Term) (ABIN453246)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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宿主

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克隆类型

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多克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 443-472, C-Term

    特异性

    This antibody recognizes Protein Disulfide Isomerase.

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 443~472 amino acids from the C-terminal region of Human P4HB. Genename: P4HB
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    PDI / P4HB

    背景

    P4HB is a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta p55, Protein disulfide-isomerase

    基因ID

    5034

    NCBI登录号

    NP_000909

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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