MTBP 抗体 (C-Term)
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Quick Overview for MTBP 抗体 (C-Term) (ABIN453200)
抗原
See all MTBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to MTBP.
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
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免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human MTBP
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MTBP (MDM2 Binding Protein (MTBP))
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别名
- MTBP
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背景
- MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.Synonyms: Mdm2, Mdm2-binding protein, hMTBP
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基因ID
- 27085
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NCBI登录号
- NP_071328
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UniProt
- Q96DY7
抗原
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