PRAME 抗体 (C-Term)
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Quick Overview for PRAME 抗体 (C-Term) (ABIN453177)
抗原
See all PRAME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to MAPE.
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
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免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human MAPE
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
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别名
- PRAME / MAPE
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背景
- MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.Synonyms: Melanoma antigen preferentially expressed in tumors, OIP-4, OIP4, OPA-interacting protein 4, Preferentially expressed antigen of melanoma
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基因ID
- 23532
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NCBI登录号
- NP_006106
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UniProt
- P78395
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途径
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
抗原
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