Coagulation Factor X 抗体 (C-Term)
-
- 抗原 See all Coagulation Factor X (F10) 抗体
- Coagulation Factor X (F10)
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Coagulation Factor X antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Coagulation factor X (F10) at C-term.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human F10
- Top Product
- Discover our top product F10 Primary Antibody
-
-
- 应用备注
-
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- Coagulation Factor X (F10)
- Abstract
- F10 产品
- 背景
- F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Synonyms: Stuart factor, Stuart-Prower factor
- 分子量
- 54732 Da
- 基因ID
- 2159
- NCBI登录号
- NP_000495
- UniProt
- P00742
-