PLEKHO1 抗体 (N-Term)
-
- 抗原 See all PLEKHO1 抗体
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
-
抗原表位
- N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PLEKHO1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects CKIP-1 at N-term.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- KLH conjugated synthetic peptide selected from the N-terminal region of human CKIP-1
- Top Product
- Discover our top product PLEKHO1 Primary Antibody
-
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) antibody
PLEKHO1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 51-170) antibodyPLEKHO1 适用: 人, 小鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 49-77), (N-Term) antibodyPLEKHO1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19797 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 143-404) antibodyPLEKHO1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-410) antibodyPLEKHO1 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 大鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
- 别名
- PLEKHO1 / CKIP1 (PLEKHO1 产品)
- 别名
- CKIP-1 antibody, OC120 antibody, 2810052M02Rik antibody, Ckip1 antibody, JZA-20 antibody, Jza2 antibody, RGD1311487 antibody, ckip-1 antibody, plekho1 antibody, si:dkey-200h23.2 antibody, pleckstrin homology domain containing O1 antibody, pleckstrin homology domain containing, family O member 1 antibody, pleckstrin homology domain containing, family O member 1a antibody, PLEKHO1 antibody, Plekho1 antibody, plekho1a antibody
- 背景
- CKIP-1 plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). This protein may function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). It appears to target ATM to the plasma membrane and appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.Synonyms: C-Jun-binding protein, CK2-interacting protein 1, CKIP-1, Casein kinase 2-interacting protein 1, HQ0024c, JBP, OC120, Osteoclast maturation-associated gene 120 protein, PH domain-containing family O member 1, Pleckstrin homology domain-containing family O member 1
- 分子量
- 46237 Da
- 基因ID
- 51177
- NCBI登录号
- NP_057358
- UniProt
- Q53GL0
-
