电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

B-Cell Linker 抗体 (Middle Region)

BLNK 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN452784
发货至: 中国
  • 抗原 See all B-Cell Linker (BLNK) 抗体
    B-Cell Linker (BLNK)
    抗原表位
    • 22
    • 19
    • 17
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 97
    • 68
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 107
    • 8
    • 1
    克隆类型
    • 107
    • 9
    多克隆
    标记
    • 50
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    This B-Cell Linker antibody is un-conjugated
    应用范围
    • 108
    • 52
    • 36
    • 26
    • 21
    • 19
    • 18
    • 8
    • 6
    • 6
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    BLNK antibody recognizes BLNK at Center.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A column followed by Peptide Affinity Purification.
    免疫原
    This BLNK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human BLNK.
    Top Product
    Discover our top product BLNK Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100approx. 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    B-Cell Linker (BLNK)
    别名
    B-Cell Linker Protein / BLNK (BLNK 产品)
    别名
    BLNK antibody, blnk antibody, MGC147045 antibody, BASH antibody, Bca antibody, Ly-57 antibody, Ly57 antibody, Lyw-57 antibody, SLP-65 antibody, AGM4 antibody, BLNK-S antibody, LY57 antibody, SLP65 antibody, bca antibody, B-cell linker antibody, B cell linker antibody, BLNK antibody, blnk antibody, Blnk antibody
    背景
    BLNK (B cell linker protein) is an adaptor molecule that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). This activation leads to an increase in the tyrosine phosphorylation of a number of proteins due to activation of nonreceptor protein tyrosine kinases (PTK) including Syk, which is responsible for the tyrosine phosphorylation of BLNK. BLNK is cytosolic protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human BLNK). Mapping of the tyrosine residues in BLNK reveal three tyrosines that bind PLC-gamma2, and two tyrosines that bind the Tec family kinase Btk, the Vav nucleotide exchange factor and the adaptor Nck.Synonyms: B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, BASH, Cytoplasmic adapter protein, SLP-65, SLP65, Src homology 2 domain-containing leukocyte protein of 65 kDa
    基因ID
    29760
    NCBI登录号
    NP_001107566
    UniProt
    Q8WV28
    途径
    BCR Signaling
You are here:
客服