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ALS2 抗体 (C-Term)

ALS2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN452733
发货至: 中国
  • 抗原 See all ALS2 抗体
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 37
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 34
    • 3
    • 1
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALS2 antibody is un-conjugated
    应用范围
    • 20
    • 14
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Alsin / ALS2 at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2
    Top Product
    Discover our top product ALS2 Primary Antibody
  • 应用备注
    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    别名
    Alsin / ALS2 (ALS2 产品)
    别名
    als2 antibody, si:dkey-33m14.1 antibody, ALS2CR6 antibody, ALSJ antibody, IAHSP antibody, PLSJ antibody, 3222402C23Rik antibody, 9430073A21Rik antibody, Als2cr6 antibody, Alsin antibody, mKIAA1563 antibody, amyotrophic lateral sclerosis 2a (juvenile) antibody, alsin antibody, ALS2, alsin Rho guanine nucleotide exchange factor antibody, amyotrophic lateral sclerosis 2 (juvenile) antibody, als2a antibody, CpipJ_CPIJ008258 antibody, CpipJ_CPIJ008260 antibody, ALS2 antibody, Als2 antibody
    背景
    ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.Synonyms: ALS2CR6, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis protein 2, KIAA1563
    分子量
    183666 Da
    基因ID
    57679
    NCBI登录号
    NP_001129217
    UniProt
    Q96Q42
    途径
    Skeletal Muscle Fiber Development
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