ALS2 抗体 (C-Term)
Quick Overview for ALS2 抗体 (C-Term) (ABIN452733)
抗原
See all ALS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Alsin / ALS2 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2
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anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibody
ALS2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibodyALS2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-320) antibodyALS2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) antibodyALS2 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibodyVerified ALS2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (N-Term) antibodyALS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1007-1056) antibodyALS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1248-1277), (C-Term) antibodyALS2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18853 unconjugated
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应用备注
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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别名
- Alsin / ALS2
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背景
- ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.Synonyms: ALS2CR6, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis protein 2, KIAA1563
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分子量
- 183666 Da
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基因ID
- 57679
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NCBI登录号
- NP_001129217
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UniProt
- Q96Q42
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途径
- Skeletal Muscle Fiber Development
抗原
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