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TNK2 抗体 (N-Term)

The 兔 多克隆 anti-TNK2 antibody is suitable to detect TNK2 in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN452711
发货至: 中国
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Quick Overview for TNK2 抗体 (N-Term) (ABIN452711)

抗原

See all TNK2 抗体
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TNK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects TNK2 / ACK1 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide selected from the N-terminal region of human ACK1
  • 应用备注

    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    别名

    TNK2 / ACK1

    背景

    ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1

    分子量

    114327 Da

    基因ID

    10188

    NCBI登录号

    NP_001010938

    UniProt

    Q07912
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