HSF2 抗体
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北京 101111
Quick Overview for HSF2 抗体 (ABIN452666)
抗原
See all HSF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat, Guinea Pig, Hamster, Monkey, Rabbit, Dog, Bovine, Sheep, Pig.
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产品特性
- Synonyms: HSF-2, HSTF2, Heat shock transcription factor 2
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纯化方法
- Purified
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免疫原
- Purified recombinant mouse SF2 protein
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亚型
- IgG1
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anti-Heat shock factor protein 2 (HSF2) (AA 401-536) antibody
HSF2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 79-173) antibodyHSF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-230) antibodyHSF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11-A3 unconjugated
anti-Heat shock factor protein 2 (HSF2) (Internal Region) antibodyHSF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 82-102), (Middle Region) antibodyHSF2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-200) antibodyHSF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 294-518) antibodyHSF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-230) antibodyHSF2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 48-97) antibodyHSF2 适用: 人, 大鼠, 兔, Cow, 豚鼠, 猴, Pig, 马, 斑马鱼, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 441-490) antibodyHSF2 适用: 人, 大鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot: 4 μg/mL was sufficient for detection of HSF2 of HeLa lysate. Gel Shift Assay (EMSA). Immunoprecipitation. Immunoflourescence. Immunohistochemistry on frozen sections. ELISA.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium Azide, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- HSF2 (Heat shock factor protein 2 (HSF2))
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别名
- Heat Shock Factor 2 / HSF2
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背景
- HSF2, or heat shock factor 2, belongs to a family of Heat Shock transcription factors that activate the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function (2). The up-regulation of HSP (heat shock proteins) expression by stressors is achieved at the level of transcription through a heat shock element (HSE) and a transcription factor (HSF) (3, 4, 5). Most HSFs have highly conserved amino acid sequences. On all HSFs there is a DNA binding domain at the Nterminus. Hydrophobic repeats located adjacent to this binding domain are essential for the formation of active trimers. Towards the C-terminal region another short hydrophobic repeat exists, and is thought to be necessary for suppression of trimerization (6). There are two main heat shock factors, 1 and 2. Mouse HSF1 exists as two isoforms, however in higher eukaryotes HSF1 is found in a diffuse cytoplasmic and nuclear distribution in un-stressed cells. Once exposed to a multitude of stressors, it localizes to discrete nuclear granules within seconds. As it recovers from stress, HSF1 dissipates from these granules to a diffuse nuceloplasmic distribution. HSF2 on the other hand is similar to mouse HSF1, as it exists as two isoforms, the alpha form being more transciptionally active than the smaller beta form (7, 8). Various experiments have suggested that HFS2 may have roles in differentiation and development (9, 10, 11).Synonyms: HSF-2, HSTF2, Heat shock transcription factor 2
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UniProt
- P38533
抗原
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