TYMS 抗体 (N-Term)
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北京 101111
Quick Overview for TYMS 抗体 (N-Term) (ABIN452662)
抗原
See all TYMS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-313, N-Term
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特异性
- The antibody recognizes human TYMS. Other species not tested.
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产品特性
- Synonyms: TYMS, TSase, OK/SW-cl.29
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant TYMS (1-313 aa) purified from E. coli
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亚型
- IgG2b
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anti-Thymidylate Synthetase (TYMS) (AA 36-313) antibody
TYMS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS 适用: 人 IF, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 60-174) antibodyTYMS 适用: 人 IF, WB, FACS, IHC, ISt, RIA, StM 宿主: 小鼠 Monoclonal TYMS-1884 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 IF, WB, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5H8 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 265-294), (C-Term) antibodyTYMS 适用: 人 IF, WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20041 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 2-54) antibodyTYMS 适用: 人 IF, WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-211) antibodyTYMS 适用: 人 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 2B2 unconjugated
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应用备注
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ELISA. Western blot (1: 500 - 1: 1,000). Immunofluorescence (1: 500 - 1: 1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TYMS (Thymidylate Synthetase (TYMS))
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别名
- Thymidylate Synthase (TS)
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背景
- The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by thymidylate synthase (TS or TYMS). TYMS is an intracellular enzyme that provides the sole de novo source of thymidylate in activity highest proliferating cells. Being the exclusive source of dTMP, TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head and neck. TS expression may be useful in predicting overall patient survival, but the prognostic value of TS expression continues to be a subject of investigation for different types of cancers.Synonyms: OK/SW-cl.29, TSase, TYMS
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基因ID
- 54583
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UniProt
- P04818
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途径
- Mitotic G1-G1/S Phases
抗原
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