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FPR2 抗体 (AA 181-192)

The 小鼠 单克隆 anti-FPR2 antibody is suitable to detect FPR2 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN452645
发货至: 中国
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Quick Overview for FPR2 抗体 (AA 181-192) (ABIN452645)

抗原

See all FPR2 抗体
FPR2 (Formyl Peptide Receptor 2 (FPR2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FPR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

B4D9B10
  • 抗原表位

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    AA 181-192

    特异性

    This monoclonal antibody reacts with the above mentioned peptide in ELISA and reacts with the 38KDa FPRL1 on Western Blot.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: N-formyl peptide receptor 2, FMLP-R-I, FPRH1, RFP, LXA4R, FMLP-related receptor I, Formylpeptide receptor-like 1, Lipoxin A4 receptor

    纯化方法

    Affinity Chromatography.

    免疫原

    A short KLH conjugated peptide corresponding to the amino acid sequence 181-192(ASWGGTPEERLK) on Human FPRL1

    亚型

    IgG1
  • 应用备注

    ELISA. Western Blot (1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL

    缓冲液

    0.01 M PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    FPR2 (Formyl Peptide Receptor 2 (FPR2))

    别名

    FPR2 / FPRL1

    背景

    FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.Synonyms: FMLP-R-I, FMLP-related receptor I, FPRH1, Formyl peptide receptor-like 1, LXA4R, Lipoxin A4 receptor, N-formyl peptide receptor 2, RFP

    基因ID

    2358

    UniProt

    P25090
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