FPR2 抗体 (AA 181-192)
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Quick Overview for FPR2 抗体 (AA 181-192) (ABIN452644)
抗原
See all FPR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 181-192
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特异性
- This monoclonal antibody reacts with the above mentioned peptide in ELISA and reacts with the 38KDa FPRL1 on Western Bloton.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: N-formyl peptide receptor 2, FMLP-R-I, FPRH1, RFP, LXA4R, FMLP-related receptor I, Formylpeptide receptor-like 1, Lipoxin A4 receptor
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纯化方法
- Affinity Chromatography.
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免疫原
- A short KLH conjugated peptide corresponding to the amino acid sequence 181-192(ASWGGTPEERLK) on Human FPRL1
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亚型
- IgG1
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应用备注
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ELISA. Western Blot (1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL
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缓冲液
- 0.01 M PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- FPR2 (Formyl Peptide Receptor 2 (FPR2))
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别名
- FPR2 / FPRL1
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背景
- Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-α by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.Synonyms: FMLP-R-I, FMLP-related receptor I, FPRH1, Formyl peptide receptor-like 1, LXA4R, Lipoxin A4 receptor, N-formyl peptide receptor 2, RFP
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基因ID
- 2358
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UniProt
- P25090
抗原
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