CGA 抗体
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北京 101111
Quick Overview for CGA 抗体 (ABIN452635)
抗原
See all CGA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is reactive to Alpha chain of Human TSH.
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产品特性
- Synonyms: Follitropin alpha chain, Follicle-stimulating hormone alpha chain, FSH-alpha, Lutropinalpha chain, Luteinizing hormone alpha chain, LSH-alpha, LH alpha, Thyrotropin alphachain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Choriogonadotropin alphachain, Chorionic gonadotrophin subunit alpha, hCG-alpha, Anterior pituitary glycoproteinhormones common subunit alpha
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Human TSH
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亚型
- IgG1
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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缓冲液
- 0.01 M PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))
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别名
- Glycoprotein Hormones alpha Chain
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背景
- Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. TSH has a alpha subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.Synonyms: Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, FSH-alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, LH alpha, LSH-alpha, Luteinizing hormone alpha chain, Lutropin alpha chain, TSH-alpha, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, hCG-alpha
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基因ID
- 1081
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UniProt
- P01215
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途径
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism
抗原
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