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CD3 抗体

CD3 适用: 人 EIA 宿主: 小鼠 Monoclonal JXT3 unconjugated
产品编号 ABIN452555
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD3 antibody is un-conjugated
    应用范围
    • 248
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    Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human peripheral blood T cell CD3 antigen.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Human peripheral T lymphocytes.
    克隆位点
    JXT3
    亚型
    IgG2a
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    缓冲液
    0.01 M PBS, pH 7.0 without preservatives.
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
    背景
    T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    基因ID
    916
    UniProt
    P07766
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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